Glufosinate ammonium, a herbicide, stimulates nitric oxide production in rat cerebellum
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منابع مشابه
Nitric oxide stimulates IP3 production via a cGMP/ PKG-dependent pathway in rat pancreatic acinar cells.
In an attempt to explore the functioning of nitric oxide (NO) in pancreatic exocrine cells, we have recently obtained several lines of circumstantial evidence indicating that one of molecular targets of NO is phospholipase C (PLC), the activation of which leads to an increase in the cytosolic Ca2+ concentration ([Ca2+]i) via inositol 1, 4, 5-trisphosphate, IP3. However, whether IP3 is actually ...
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Systemic hypotension during sepsis is thought to be due to nitric oxide (NO) overproduction, but it may also be due to acidosis. We evaluated in healthy rats the consequences of acid infusion on NO and blood pressure. Sprague-Dawley rats were anesthetized, and ventilated with room air. The animals were randomized into four groups. Group 1 (C, n = 10) received only normal saline at rates compara...
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Renal ischemia in humans and in experimental animals is associated with a complex and possibly interrelated series of events. In this study, we have investigated the glomerular nitric oxide (NO) production after renal ischemia. Unilateral or bilateral renal ischemia was induced in Wistar rats by clamping one or both renal arteries. NO production was assessed by measuring glomerular production o...
متن کاملCadmium Stress Stimulates Nitric Oxide Production by Wheat Roots
Study was conducted to elucidate the nitrite-dependent nitric oxide (NO) production by wheat roots grown in hydroponics under cadmium (Cd) stress. In a long-term Cd exposure experiment, plants were grown for 4 weeks under 1 μM Cd. The root Cd concentration in the Cd-stressed plants was 2.5 mM compared to 0.1 mM in the untreated plants. Most of the Cd taken up by plants was restricted to roots w...
متن کاملAdrenomedullin stimulates nitric oxide production from primary rat hypothalamic neurons: roles of calcium and phosphatases.
Adrenomedullin (ADM) in the brain plays important roles in the maintenance of homeostasis. Although in vivo evidence has suggested that nitric oxide (NO) mediates ADM's effects in the brain, mechanisms for ADM stimulation of NO production in neurons have not been identified. In the present study, primary hypothalamic neurons were used to characterize ADM-induced NO production and to study the u...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1999
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)34190-3